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. 2014 Sep 25;16:443. doi: 10.1186/s13058-014-0443-5

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© Tornillo et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. The licensee has exclusive rights to distribute this article, in any medium, for 6 months following its publication. After this time, the article is available under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Schematic representation of the mechanisms of Aurora-A kinase regulation by Nedd9 and major effects of Nedd9 up-regulation mediated by Aurora-A kinase in breast cancer cells. AurA, Aurora-A; CTTN, cortactin; Ub, ubiquitin.