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. 2015 Mar 17;12:19. doi: 10.1186/s12950-015-0063-6

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© Soufli et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Pretreatment with hydatid LL protects colonic goblet cells in DSS-induced colitis. A, Representative photomicrographs of Alcian blue stained colonic tissue. (a) CTRL group: normal crypts and important mucus secretion, (b) DSS group: total depletion of goblet cells accompanied by the absence of mucus, (c) LL + DSS group: normal crypts and secretion of mucus by the goblet cells. (d) LL group: normal crypts, presence of a number of goblet cells secreting mucus. B, Changes in goblet cells number. All results are expressed as the mean ± standard error of the mean. p values from LSD post-hoc ANOVA test are indicated (***p < 0.001, ****p < 0.0001). GC: Goblet Cells.