Table 2.
Virulence genes associated with pathogenicity present in ETEC O157
| Type | Gene | O157 SvETEC | O157:K88 734/3 | Details |
|---|---|---|---|---|
| Adhesins | faeG | + | + | K88 (F4) Fimbrial adhesin |
| fimH | + | + | Type 1 fimbriae, D-Mannose-specific adhesin | |
| csgG | + | + | Facilitator of fibronectin-binding curli assembly | |
| eaeH | + | + | Highly conserved adhesin | |
| sfmA | + | + | Fimbrial-like adhesin | |
| ecpA | + | + | E. coli common pilus | |
| mat | + | + | mat operon | |
| Toxins | east1 | + | + | Enteroaggregative E. coli heat-stable enterotoxin |
| hlyA | + | + | α-Hemolysin | |
| hlyE | + | + | Hemolysin E | |
| eltB | + | + | Heat-labile enterotoxin B subunit | |
| eltA | + | + | Heat-labile enterotoxin A subunit | |
| estA | + | Heat-stable enterotoxin a | ||
| estB | + | + | Heat-stable Enterotoxin b | |
| estB | + | Heat-stable Enterotoxin b (second allele) | ||
| Siderophores | fyuA | + | + | Iron uptake receptor |
| irp2 | + | + | Iron repressible protein | |
| Other | bor | + | Serum survival | |
| traT | + | + | Surface exclusion and serum survival | |
| fliC | + | + | Flagellin structural protein, H antigen determinant (H19 allele) |