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. 2015 Mar 16;16(1):89. doi: 10.1186/s12859-015-0524-1

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© Schuette et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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A bait and prey method was used to reconstruct a sub-network using the Physcomitrella predicted interactome. Two proteins known to be involved in the Calvin-Benson-Bassham cycle were used as bait (blue color nodes) and their first neighbors are the captured prey (green color nodes). These two known CBB-cycle proteins do not directly interact, but interact with several other proteins that serve as intermediates. Additional file 8: Table S7 contains the complete protein list and annotations used for this analysis.