Table 7.
Numerical and percentage distribution of VEGFR-1/pVEGFR-1 co-expression in the vasculature
| N0/M0 n (%) | N+ n (%) | N0/M0 vs. N + p | M+ n (%) | N0/M0 vs. M + p | ||
|---|---|---|---|---|---|---|
| VEGFR1+/pVEGFR-1 Tyr1048 + | ||||||
| Capillaries | zone 1 | 22/9 (41) | 10/4 (40) | NS 1.0 | 14/7 (50) | NS 0.7 |
| zone 2 | 28/11 (39) | 13/8 (62) | NS 0.3 | 19/13 (68) | NS 0.08 | |
| zone 3 | 21/12 (57) | 12/8 (67) | NS 0.7 | 11/5 (45) | NS 0.7 | |
| small vessels | zone 1 | 23/19 (83) | 11/4 (36) | 0.01 | 12/5 (42) | 0.02 |
| zone 2 | 29/20 (69) | 15/12 (80) | NS 0.5 | 17/14 (82) | NS 0.5 | |
| zone 3 | 27/22 (81) | 14/13 (93) | NS 0.6 | 13/7 (54) | NS 0.2 | |
| VEGFR-1+/pVEGFR-1 Tyr1213 + | ||||||
| Capillaries | zone 1 | 21/6 (28) | 8/2 (25) | NS 1.0 | 14/2 (14) | NS 0.4 |
| zone 2 | 27/7 (26) | 12/3 (25) | NS 1.0 | 18/1 (6) | NS 0.1 | |
| zone 3 | 27/16 (59) | 14/5 (36) | NS 0.2 | 13/7 (54) | NS 1.0 | |
| small vessels | zone 1 | 22/12 (55) | 11/3 (27) | NS 0.3 | 11/2 (18) | 0.05 |
| zone 2 | 28/13 (46) | 16/8 (50) | NS 1.0 | 16/2 (13) | 0.04 | |
| zone 3 | 27/16 (59) | 14/5 (36) | NS 0.2 | 13/7 (54) | NS 1.0 | |
n: total number of VEGFR-1 positive cases/total number of pVEGFR-1 positive cases with concomitant VEGFR-1 positivity. p < 0.05 statistically significant, NS not significant.