Table 2.

Cardiovascular risk biomarkers and ACE-inhibition.

	N	Fosinopril	Placebo	p
Angiotensin-II (pg/mL)	192	11.10 (7.10–17.90)	12.50 (7.70–19.40)	<0.001
C-Reactive protein (mg/L)	243	2.40 (1.03–5.07)	2.34 (1.17–4.89)	0.62
Interleukin-6 (pg/mL)	246	2.37 (1.72–3.85)	2.54 (1.75–3.80)	0.89
Plasminogen activator inhibitor-1 (ng/mL)	247	25.95 (16.50–40.96)	25.77 (16.42–45.60)	0.70
D-Dimer (µg/mL)	238	0.32 (0.22–0.53)	0.29 (0.20–0.50)	0.02
Vascular cell adhesion molecule-1 (ng/mL)	236	1057.0 (832.2–1331.7)	1054.5 (830.7–1319.5)	0.98
Endothelin-1 (pg/mL)	236	1.52 (1.21–1.84)	1.49 (1.26–1.85)	0.62

Values are expressed as median (interquartile range) and p values calculated using log-transformed values and t-test analyses.