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Reaction conditions and radiochemical yields for [11C]LAAM
| Solvent | Methylation source / base / reaction temperature | Radiochemical yield |
|---|---|---|
| DMSO | [11C]MeI / 5N NaOH/ 85°C | 41% |
| DMSO | [11C]MeI / 1M Cs2CO3/ 85°C | 25% |
| DMSO | [11C]MeOTf / 5N NaOH/ 60°C | 52% |
| MEK | [11C]MeOTf / 5N NaOH/ 60°C | 58% |
| MEK | [11C]MeOTf / 30% KOH/ 60°C | 63% |
