Table 3.

Biodistribution of [¹¹C]LAAM in male Swiss-Webster mice^*.

Organ	5 min	15 min	30 min	60 min	90 min
blood	1.11 ± 0.16	1.05 ± 0.09	0.93 ± 0.10	1.10 ± 0.10	1.19 ± 0.11
lung	67.75 ± 7.28	53.16 ± 10.42	30.07 ± 2.77	19.12 ± 1.84	12.94 ± 2.61
liver	8.43 ± 0.96	8.92 ± 1.29	9.73 ± 1.76	8.55 ± 1.31	7.38 ± 1.07
spleen	6.43 ± 1.06	9.72 ± 2.08	8.88 ± 0.57	5.75 ± 0.69	4.49 ± 0.69
kidney	21.30 ± 1.26	16.58 ± 2.82	12.41 ± 1.69	6.78 ± 0.52	4.59 ± 0.60
bladder	1.92 ± 0.90	3.23 ± 0.72	6.38 ± 3.84	3.20 ± 1.32	3.57 ± 1.35
gall bladder	2.68 ± 0.47	3.62 ± 1.13	7.28 ± 3.03	13.16 ± 6.77	22.18 ± 5.72
muscle	4.22 ± 0.37	3.07 ±±0.65	1.96 ± 0.24	1.41 ± 0.12	1.01 ± 0.21
fat	2.32 ± 1.35	2.33 ± 0.58	3.72 ± 0.52	3.62 ± 0.74	4.79 ± 1.64
Heart	7.56 ± 1.14	4.56 ± 0.93	3.11 ± 0.75	1.85 ± 0.40	1.58 ± 0.60
brain	1.81 ± 0.14	1.91 ± 0.32	1.52 ± 0.13	1.07 ± 0.09	0.94 ± 0.15
bone	2.76 ± 0.43	3.51 ± 0.65	3.18 ± 0.42	2.01 ± 0.38	2.43 ± 1.05
marrow	2.91 ± 1.33	1.93 ± 1.19	2.07 ± 1.50	3.79 ± 3.17	3.26 ± 7.09
testes	1.32 ± 0.08	1.80 ± 0.35	2.06 ± 0.14	2.60 ± 0.43	2.42 ± 0.66
prostate	2.12 ± 0.77	2.82 ± 0.48	3.27 ± 1.65	2.17 ± 1.17	2.63 ± 0.97
adrenals	14.35 ± 0.59	8.68 ± 3.54	8.80 ± 1.82	4.78 ± 0.94	4.01 ± 3.66
thyroid	4.90 ± 0.31	3.97 ± 0.33	3.46 ± 0.58	2.26 ± 0.40	3.01 ± 1.82
pancreas	9.84 ± 1.69	8.13 ± 2.14	7.35 ± 1.03	5.44 ± 0.55	4.94 ± 0.69
thymus	4.93 ± 0.97	5.15 ± 1.33	4.88 ± 0.68	3.65 ± 0.65	2.16 ± 0.94
stomach	3.21 ± 0.68	3.68 ± 1.06	4.58 ± 0.38	3.36 ± 0.94	3.29 ± 0.74
small intestine	5.74 ± 0.41	6.76 ± 0.72	7.97 ± 0.85	7.05 ± 1.25	5.89 ± 0.89
upper large intestine	3.61 ± 0.17	4.53 ± 0.62	4.49 ± 0.37	6.13 ± 0.95	8.26 ± 1.66
lower large intestine	2.19 ± 0.14	2.30 ± 0.56	2.56 ± 0.08	2.22 ± 0.18	2.16 ± 0.35
skin	1.50 ± 0.10	2.02 ± 0.37	2.26 ± 0.21	2.35 ± 0.39	2.00 ± 0.49

^*results are expressed as percent injected dose per gram of tissue (%ID/g) and are the mean ± standard deviation (n=4).