Table 4.
Patient age and laboratory values of the study cohort, by consensus diagnosis (n=149)
| n | Mean | Median | Min | Max | p-value* | |
|---|---|---|---|---|---|---|
| Age at diagnosis (in years) | ||||||
| All enrolled patients | 149 | 9.3 | 8.8 | 0 | 21.1 | |
| Patients with consensus diagnosis | 68 | 9.9 | 9.0 | 1.5 | 20.4 | |
| AA | 28 | 9.4 | 8.3 | 3.5 | 19.8 | 0.4 |
| RCC | 30 | 10.6 | 10.6 | 1.5 | 20.0 | |
| Other | 10 | 9.3 | 6.3 | 1.8 | 20.4 | |
| Follow up years | ||||||
| All enrolled patients | 149 | 4.2 | 2.6 | 0.02 | 21.5 | |
| Patients with consensus diagnosis | 68 | 4.2 | 3.1 | 0.2 | 17.7 | |
| AA | 28 | 3.8 | 2.4 | 0.2 | 16.1 | 0.3 |
| RCC | 30 | 4.7 | 3.7 | 0.2 | 17.7 | |
| Other | 10 | 4.1 | 2.5 | 0.3 | 16.0 | |
| Laboratory values | ||||||
| WBC | ||||||
| All enrolled patients | 144 | 2.8 | 2.6 | 0.5 | 12.0 | |
| Total | 68 | 2.7 | 2.5 | 0.5 | 9.1 | |
| AA | 28 | 2.4 | 2.1 | 0.5 | 5.4 | 0.1 |
| RCC | 30 | 2.7 | 2.8 | 0.9 | 5.4 | |
| Other | 10 | 3.5 | 2.6 | 0.5 | 9.1 | |
| ANC | ||||||
| All enrolled patients | 139 | 331.3 | 1.1 | 0 | 7333.0 | |
| Total | 64 | 338.6 | 1.1 | 0 | 7333.0 | |
| AA | 26 | 332.9 | 0.8 | 0 | 3255.0 | 0.7 |
| RCC | 29 | 193.7 | 1.2 | 0 | 2100.0 | |
| Other | 9 | 821.9 | 0.6 | 0 | 7333.0 | |
| Hgb | ||||||
| All enrolled patients | 128 | 7.4 | 7.8 | 2.0 | 14.3 | |
| Total | 60 | 7.6 | 7.8 | 2.4 | 14.3 | |
| AA | 23 | 6.4 | 6.6 | 2.4 | 10.2 | 0.03 |
| RCC | 28 | 8.1 | 8.1 | 2.7 | 13.7 | |
| Other | 9 | 9.1 | 8.8 | 5.0 | 14.3 | |
| Platelet count | ||||||
| All enrolled patients | 148 | 15.8 | 9.0 | 1.0 | 103.0 | |
| Total | 68 | 16.8 | 9.0 | 1.0 | 103.0 | |
| AA | 28 | 11.4 | 7.5 | 1.0 | 52.0 | 0.2 |
| RCC | 30 | 19.9 | 9.5 | 1.0 | 103.0 | |
| Other | 10 | 22.9 | 11.5 | 3.0 | 90.0 | |
| MCV | ||||||
| All enrolled patients | 116 | 89.1 | 88.5 | 60.0 | 115.0 | |
| Total | 56 | 88.4 | 87.0 | 60.0 | 111.0 | |
| AA | 23 | 86.3 | 85.0 | 60.0 | 110.0 | 0.1 |
| RCC | 26 | 91.0 | 92.5 | 76.0 | 111.0 | |
| Other | 7 | 86.0 | 85.0 | 72.0 | 105.0 | |
| Absolute reticulocyte count | ||||||
| All enrolled patients | 68 | 0.030 | 0.019 | 0 | 0.215 | |
| Total | 38 | 0.030 | 0.022 | 0 | 0.092 | |
| AA | 14 | 0.011 | 0.009 | 0 | 0.030 | 0.005 |
| RCC | 19 | 0.038 | 0.035 | 0 | 0.092 | |
| Other | 5 | 0.05 | 0.048 | 0.022 | 0.089 | |
| Hemoglobin F | ||||||
| All enrolled patients | 55 | 4.0 | 2.4 | 0 | 20.4 | |
| Total | 29 | 3.4 | 2.4 | 0 | 13.2 | |
| AA | 11 | 2.9 | 1.2 | 0 | 10.6 | 0.4 |
| RCC | 14 | 4.1 | 3.0 | 0 | 13.2 | |
| Other | 4 | 2.4 | 2.2 | 0.7 | 4.4 | |
*
p-value of Wilcoxon rank sums test comparing AA and RCC
“Total” refers to all patients with consensus diagnosis and available data.