Table 1.

Statistical analysis of the correlation between number of genes and maximum lifespan, corrected for phylogeny

DOI: http://dx.doi.org/10.7554/eLife.06184.007

Gene family	PGLS	FIC
Tree I
CD33rSIGLECs	0.00016	0.00012
KLKs	0.49	0.17
TLRs	0.38	0.10
IgG Fc receptors	0.35	0.0016
Tree II
CD33rSIGLECs	0.00017	0.00011
KLKs	0.65	0.23
TLRs	0.32	0.14
IgG Fc receptors	0.39	0.0019

Phylogenetic comparative analysis was conducted in COMPARE 4.6b using Phylogeny Generalized Least-Squares (PGLS) or Felsenstein's Independent Contrast (FIC) approaches. Student's t-values were computed based on the regression slopes and the standard errors. Two-tailed probability (p) value of a Student's t-test was estimated using a degree of freedom of 11. The phylogenetic relationship of 14 mammalian species represented by Tree I and Tree II are indicated in Figure 1—figure supplement 3. Note that although FIC analysis obtained a significant p value for IgG Fc receptor gene family, the p value increased to 0.56 when human data was excluded. Thus, this correlation is driven by one outlier data point.