Table 2. Statistical analysis of the correlation between number of genes and maximum lifespan, corrected for body weight.
| Gene family | t value | p value |
|---|---|---|
| Tree I | ||
| CD33rSIGLECs | 3.521435 | 0.004786 |
| KLKs | 0.360601 | 0.725226 |
| TLRs | −0.701822 | 0.497370 |
| IgG Fc receptors | 1.656519 | 0.125834 |
| Tree II | ||
| CD33rSIGLECs | 3.660917 | 0.003748 |
| KLKs | 0.180227 | 0.860251 |
| TLRs | −0.726465 | 0.482726 |
| IgG Fc receptors | 1.589586 | 0.140235 |
Phylogenetic comparative analysis conducted in CAIC package. Average adult body weight and maximum lifespan of 14 mammalian species were log-transformed and phylogenetic regressions were run using pglmEstLambda in the CAIC package in R. This function uses the PGLS method and estimates λ with the average adult body weight controlled for. Student's t-values and two-tailed probability (p) values are shown. The phylogenetic relationship of 14 mammalian species represented by Tree I and Tree II are indicated in Figure 1—figure supplement 3.