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. Author manuscript; available in PMC: 2015 Apr 3.
Published in final edited form as: Eur J Neurosci. 2011 Nov 18;34(11):1737–1746. doi: 10.1111/j.1460-9568.2011.07891.x

Fig. 3.

Fig. 3

Effect of RhoB deletion on nuclear morphology in corticohippocampal neurons following exposure to STS. (A) DAPI staining (blue) of corticohip-pocampal neurons from WT or RhoB KO mice 24 h following exposure to 500 nm STS. Scale bar = 10 µm. Note the higher proportion of nuclei showing condensation in the neurons lacking RhoB. (B,C) Nuclear morphology in corticohippocampal neurons from WT or RhoB KO mice 6 h (B) or 24 h (C) following exposure to STS. Results are shown as mean ± SEM, n = 3–5 per group. (B) Two-way anova: effect of STS concentration – F3,39 = 48.71, P < 0.001; effect of genotype – F3,39 = 39.71, P < 0.001. (C) Two-way anova: effect of STS dose – F3,39 = 254.38, P < 0.001; effect of genotype – F1,39 = 159.21, P < 0.001; **P < 0.01; post-hoc Tukey’s test vs. corresponding WT group. For interpretation of color references in figure legend, please refer to the Web version of this article.

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