Fig. 6.

Altered Bax expression in corticohippocampal neurons lacking RhoB. (A) Western blot showing expression of Bax and actin (loading control) in extracts from cortico-hippocampal cultures treated for 2 h with either vehicle or 500 nm STS. (B) Quantification of Bax immunoblotting in primary cortico-hippocampal cultures from WT and RhoB KO mice, treated for 2 h with either vehicle or 500 nm STS. Results are shown as mean ± SEM, n = 3 per group. Two-way anova: effect of STS concentration – F_1,10 = 10.4, P = 0.015; effect of genotype – F_1,10 = 10.0, P = 0.016; no significant interaction. *P < 0.05; **P < 0.01 vs. corresponding WT vehicle.