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RhoB deletion modulates caspase 3 activity in adult brain. Caspase 3 activity in cortex and cerebellum samples from WT and RhoB KO (KO) mouse brain (aged 4 months). Results are shown as mean ± SEM, n = 4–5 per group. Activity in tissue from RhoB KO mice was significantly reduced relative to WT mice (two-way anova – factors: genotype and tissue; caspase 3 activity: effect of genotype F1,16 = 9.93, P = 0.008; *P < 0.05 relative to corresponding WT samples, post-hoc Tukey’s test.
