FIG. 7.

T₁ measurements of NAD⁺, NADH, and α-ATP in normal cat brains with a total of nine different inversion-recovery time values acquired at 16.4 T and 9.4 T. a: Model fittings (red lines) to the in vivo ³¹P spectra (gray lines) of a representative cat brain with 24 signal averages obtained at 16.4 T. b: Model fittings (red lines) to the summed spectra (gray lines) from five cat brains with total 96 signal averages acquired at 16.4 T. c and d: Model decomposed individual signals of NAD⁺ (amplification × 7) and NADH (amplification × 9) from (b) (amplification × 1). e: Exponential fittings of the T₁ data: based on the model fitting of summed spectra at 9.4 T (left, N = 7, total NT = 88) and 16.4 T (right, N = 5, total NT = 96). Measured T₁ values of NAD⁺, NADH, and α-ATP are: 1.58, 1.50, and 0.90 s at 9.4 T; 0.82, 0.87, and 0.57 s at 16.4 T, respectively.