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. Author manuscript; available in PMC: 2015 Nov 20.
Published in final edited form as: Immunity. 2014 Nov 5;41(5):830–842. doi: 10.1016/j.immuni.2014.10.017

Figure 2. Tmem173−/−Mice andIrf3−/−Mice Show Defective Tumor Control.

Figure 2

(A and B) 1969 tumor cells were inoculated into WT, Tmem173−/−, or Irf3−/− mice and tumor growth was recorded on the indicated days.

(C) WT or Tmem173−/− mice (129 background) were inoculated with 106 B16.SIY melanoma cells and tumor size was measured over time.

(D–F) B16.SIY tumor cells (106 cells per mouse) were injected into the indicated mice subcutaneously, and tumor growth was measured on the indicated days.

*p < 0.05, **p < 0.01, ***p < 0.001 (Student’s t test). Data represent mean ± SEM and representative of at least two independent experiments.