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. Author manuscript; available in PMC: 2015 Apr 3.
Published in final edited form as: Cancer Res. 2012 Aug 6;72(16):3987–3996. doi: 10.1158/0008-5472.CAN-12-1337

Fig. 1. Occult tumors persist in equilibrium.

Fig. 1

Groups of 20–32 male C57BL/6 WT mice were inoculated subcutaneously with 25 μg MCA. At (A, B) 200 days, (C, D) 300 days, or (E, F) 400 days the tumor-free mice were injected weekly for 8 weeks with (A, C, E) cIg (PIP2, 300 μg i.p.) or (B, D, F) a cocktail of anti-CD4/-CD8/-IFN-γ (100 μg i.p. each). Mice were monitored for the appearance of late-forming sarcomas for 200 days after the commencement of antibody treatment. The proportion of tumors arising prior and post mAb treatment are indicated. Tumor size (cm2) for each individual mouse is plotted.