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Cytotoxicity of DOX-incorporated FAPuLG nanoparticles against KB cells (*, ** = p < 0.05). KB cells were pre-treated with folic acid 1 h before drug treatment, and then, cells were exposed to 50 μg/ml of DOX or nanoparticles for 4 h. Twenty-four hours later, viable cells were determined using the MTT assay.
