Streamline and CTC deformation behavior for flow rate of 7 nl/s, 77 nl/s, and 140 nl/s for cervical cancer, respectively. (a) CTC deformation at low flow rate (7 nl/s), the squeezing regime dominated by Young-Laplace equation. (b) CTC deformation at optimum flow rate (77 nl/s). If a higher flow rate is used, the cell may detach from the filter and allow carrier fluid co-flow through the filtration channel. (c) CTC deformation at high flow rate (140 nl/s). Carrier fluid exhibits co-flows while the CTC passes through the channel.