Table 5.
Changes in biochemical parameters from serum of orally treated rats with nanocomposite
| Group | ALT U / L | ALP U / L | AST U / L | CK U / L | ALT / AST ratio | Creat μmol / L | GGT | Urea Mmol / L | Na Mmol / L | K Mmol / L | Cl Mmol / L |
|---|---|---|---|---|---|---|---|---|---|---|---|
| ZAL | 66 ± 17 | 256 ± 18 | 152 ± 30 | 3,889 ± 71 | 0.43 ± 0.03 | 48 ± 1 | <3 | 7 ± 1 | 142 ± 4 | 9 ± 1 | 102 ± 3 |
| ZA | 61 ± 6 | 293 ± 38 | 111 ± 18 | 3,398 ± 187 | 0.55 ± 0.06 | 47 ± 8 | <3 | 6 ± 1 | 145 ± 12 | 8 ± 1 | 103 ± 10 |
| VC | 59 ± 8 | 312 ± 40 | 114 ± 11 | 4,410 ± 364 | 0.51 ± 0.02 | 46 ± 4 | <3 | 6 | 143 ± 2 | 8 ± 1 | 101 ± 1 |
All data are expressed as means ± SD, and groups were compared using one-way ANOVA (n = 5) for any statistical difference between and within groups. Differences with P < 0.05 are considered statistically significant, but none of the parameters measured were found to be significantly different compared to the control group (P > 0.05). ALT, alanine aminotransferase; AST, aspartate aminotransferase; CK, creatine kinase; Creat, creatinine; GGT, gamma-glutamyltransferase; Na, sodium; K, potassium; Cl, chloride.
Microscopic appearance of liver stained with H&E.