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. Author manuscript; available in PMC: 2016 Apr 15.
Published in final edited form as: Dev Biol. 2015 Feb 23;400(2):180–190. doi: 10.1016/j.ydbio.2015.02.010

Figure 5. Comparison of the size and volume of the palatine bone at E18.5.

Figure 5

A–I: Isolated palatine bone from control (A–C), Tgfbr2fl/fl;Wnt1-Cre (R2 CKO; D–F), Tgfbr2fl/fl;Wnt1-Cre;Alk5fl/+ mice (R2 CKO;R1+/−; G–I) mice. P←→A: Posterior to Anterior J: Quantification of the size (length, width, height, and distance) of the palatine bone from control (blue bars), Tgfbr2fl/fl;Wnt1-Cre (red bars), and Tgfbr2fl/fl;Wnt1-Cre;Alk5fl/+ (green bars) mice. *p<0.01. K: Quantification of the volume of the palatine bone from control (blue bar), Tgfbr2fl/fl;Wnt1-Cre (red bar), and Tgfbr2fl/fl;Wnt1-Cre;Alk5fl/+ (green bar) mice. *p<0.01. Definitions of landmarks: 1. Most anterio-lateral point of the palatine plate; 2. Tip of the orbital process; 3. Lateral point of the palatine bone; 4. Posterior point of the palatine bone; 5. Posterior-medial point of the horizontal plate of the palatine bone; 6. Anterior-medial point of the horizontal plate of the palatine bone; 7. Anterior superior point of the perpendicular plate. Scale bar: 1 millimeter.