Table 3.
Values of Spearman’s coefficient for correlation between expression of insulin-like growth factor-1, insulin-like growth factor-1R mRNAs, and clinical data in hepatitis C virus-infected patients
| Class 1 (P1) | Class 2 (P2) | IGF-1A | IGF-1B | IGF-1C | Total IGF-1 | IGF-1R | |
| Age (yr) | -0.5451 | -0.6441 | -0.5821 | -0.6541 | -0.5321 | -0.5961 | 0.3721 |
| BMI | -0.5271 | -0.4521 | -0.4681 | -0.4141 | -0.4891 | -0.4681 | 0.060 |
| Grading | -0.4311 | -0.5691 | -0.4461 | -0.4301 | -0.2851 | -0.4571 | 0.4561 |
| Staging | -0.223 | -0.3461 | -0.182 | -0.187 | -0.160 | -0.190 | 0.264 |
| Steatosis (%) | -0.4151 | -0.5711 | -0.4121 | -0.4081 | -0.4541 | -0.4221 | 0.125 |
| ALT (U/L) | -0.5381 | -0.6161 | -0.5401 | -0.5771 | -0.5331 | -0.5501 | 0.181 |
| AST (U/L) | -0.4341 | -0.5691 | -0.3781 | -0.4001 | -0.3421 | -0.3921 | 0.212 |
| AFP (ng/mL) | -0.291 | -0.3901 | -0.168 | -0.271 | -0.240 | -0.180 | 0.311 |
| HCV RNA (IU/mL) | -0.330 | -0.3881 | -0.3571 | -0.244 | -0.096 | -0.3451 | 0.4031 |
| Total protein (g/dL) | 0.302 | 0.251 | 0.324 | 0.3751 | 0.3661 | 0.319 | 0.141 |
| Albumins (g/dL) | 0.293 | 0.3811 | 0.303 | 0.3491 | 0.222 | 0.295 | 0.123 |
| Gamma globulins (g/dL) | -0.061 | -0.164 | 0.039 | 0.045 | 0.174 | 0.044 | 0.138 |
| Blood platelets (G/L) | 0.273 | 0.3721 | 0.235 | 0.265 | 0.138 | 0.232 | -0.099 |
| Cholesterol (mg/dL) | 0.3861 | 0.286 | 0.4091 | 0.4051 | 0.372 | 0.4041 | 0.048 |
| GGTP (U/L) | -0.384 | -0.6031 | -0.284 | -0.399 | -0.367 | -0.307 | 0.330 |
| Blood glucose (mg/dL) | -0.083 | -0.226 | -0.190 | -0.112 | -0.084 | -0.201 | 0.152 |
| HOMA-IR | -0.067 | -0.157 | -0.237 | -0.140 | -0.184 | -0.234 | -0.019 |
| Insulin (μU/mL) | -0.020 | -0.082 | -0.145 | -0.079 | -0.125 | -0.135 | -0.045 |
1
The numbers indicate values of r coefficient for which the P < 0.05. IGF-1: Insulin-like growth factor 1; HCV: Hepatitis C virus; AFP: Alpha fetoprotein.