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. 2015 Apr 7;21(13):4096–4100. doi: 10.3748/wjg.v21.i13.4096

Table 1.

Possible etiology for thrombosis

Description Cause
I. Injury of vascular endothelial cells Mechanical (atherosclerosis), chemical (medication), or biologic (endotoxin)
II. Increase in platelet amount and activity Thrombocytosis, injuries caused by mechanical, chemical, or immune factors
III. Increased blood coagulation Pregnancy, advanced age, trauma, or tumor
IV. Decreased anticoagulant activity Decreased antithrombin, protein C, S, or vitamin B12 deficiency, hyperhomocysteinemia
V. Decrease of fibrinolytic activities Abnormality of plasminogen activator release or increased inhibition
VI. Abnormality of hemorheology Hyperfibrinogenemia, hyperlipidemia, dehydration, or polycythemia