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. 2015 Mar 22;2015:481972. doi: 10.1155/2015/481972

Table 3.

Comparisons of TLR2 and TLR4 mRNA expression levels according to cagA and vacA genotypes of H. pylori in infected patients before and after bacteria eradication treatment.

TLR2 TLR4
Samples (%) RQ median (range) P value Samples (%) RQ median (range) P value
Before treatment
cagA+ 11/23 (48.0) 1.32 11/23 (48.0) 1.75 0.689
0.66–23.05 0.518 0.65–11.09
cagA− 12/23 (52.0) 1.41 12/23 (52.0) 1.80
0.71–12.63 0.97–7.17
vacA s1m1 12/25 (48.0) 1.51 12/25 (48.0) 1.97 0.978
0.67–12.63 0.849 0.65–7.17
vacA others 13/25 (52.0) 1.31 13/25 (52.0) 2.02
0.66–23.05 0.97–11.09
After treatment
 Eradicated
   cagA+ 5/11 (46.0) 1.55 5/12 (42.0) 1.61 0.876
0.50–7.21 0.662 1.06–12.01
   cagA− 6/11 (54.0) 2.16 7/12 (58.0) 2.69
0.59–43.12 0.64–28.07
   vacA s1m1 7/13 (54.0) 0.71 7/13 (54.0) 1.42 0.234
0.34–7.21 0.234 0.64–12.01
   vacA others 6/13 (46.0) 2.65 6/13 (46.0) 3.30
0.59–43.12 0.89–28.07
 Noneradicated
   cagA+ 6/12 (50.0) 1.87 6/10 (60.0) 1.99 0.762
1.03–5.61 0.699 0.56–3.92
   cagA− 6/12 (50.0) 1.34 4/10 (40.0) 2.59
0.37–6.36 0.82–9.75
   vacA s1m1 5/12 (42.0) 1.36 4/11 (36.4) 1.66 0.230
0.65–5.61 0.639 0.56–2.99
   vacA others 7/12 (58.0) 1.92 7/11 (63.6) 3.52
0.37–6.36 0.82–9.75

vacAothers (s1m2, s2m2, s1_, s2_, and _m1); P value = Mann-Whitney test; P < 0.05.