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. Author manuscript; available in PMC: 2015 Apr 5.
Published in final edited form as: J Biosci. 2014 Sep;39(4):555–563. doi: 10.1007/s12038-014-9447-7

Figure 4.

Figure 4

(A) Amino acid sequence alignment of the alternatively spliced gene products Or46aA and Or46a1. (B) Representative traces showing the electrophysiological responses of ORNs. The top trace shows that there is no response to 4-methylphenol from the Δab3A neuron that ectopically expresses Or46a1. The bottom trace shows responses from the Δab3A neuron that is ectopically expressing Or46aA, upon 0.5 s stimulation (bar) with odorant 4-methylphenol. (C) Schematic of AgOr1 with location of Motif 1 indicated in red. The black letters indicate the three point mutations generated in the Motif 1 region to produce AgOrX. (D) Dose response curves showing the responses of AgOr1 and AgOrX to 4-methylphenol when expressed ectopically in the Δab3A ORNs of Drosophila. The values on the Y-axis represent the average spikes/second response to the odor stimulus minus the average spontaneous spiking frequency for each genotype. (E) Spontaneous firing rates of Δab3A neurons ectopically expressing AgOr1 and AgOrX.