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. Author manuscript; available in PMC: 2015 Dec 15.
Published in final edited form as: Psychiatry Res. 2014 Aug 1;220(0):404–409. doi: 10.1016/j.psychres.2014.07.053

Table 3. Proportion of variance in liability to male offspring psychopathology.

Diagnosis Variance (%) (95% CI)

A C E D S
INT 14 (0-32) 8 (0-28) 67 (58-77) 2 (0-12) 8 (2-18)
MD 24 (0-40) 7 (0-32) 59 (49-70) 0 (0-5) 11 (4-22)
GAD 9 (0-31) 8 (0-26) 78 (64-90) 1 (0-11) 4 (1-13)
Phobia 20 (0-32) 0 (0-24) 73 (62-86) 4 (0-16) 2 (0-9)
Panic disorder 38 (0-66) 0 (0-52) 52 (25-88) 1 (0-36) 9 (1-31)
EXT 54 (27-62) 2 (0-25) 29 (23-37) 6 (0-20) 9 (2-20)
Alcohol dependence 45 (13-57) 3 (0-30) 41 (32-51) 5 (0-19) 6 (1-15)
Drug abuse 66 (38-74) 2 (0-27) 21 (15-28) 0 (0-7) 11 (3-24)
Drug dependence 62 (17-71) 0 (0-38) 27 (17-41) 0 (0-10) 11 (2-27)

A, additive genetic effects; C, shared environmental effects; E, non-shared environmental effects.

D, parental death; S, parental separation.

CI, confidence intervals; MD, major epression; GAD, generalized anxiety disorder.

INT, internalizing disorders including MD, GAD, phobia, and panic disorder.

EXT, externalizing disorders including alcohhol dependence and drug abuse/dependence.

The values for age are not shown because it accounted for less than 0.1% of the variance.