Bar charts show mean ± standard error of mean (SEM) of mRNA levels for SOCS-1, SOCS-2, SOCS-3, SOCS-4, SOCS-5, SOCS-6, SOCS-7 and CIS following 24 hour-treatment of human microglia (n=4 cases) with indicated doses of aggregated Aβ (1–42). Significant differences between treatment and control cultures indicated. Statistical analysis one-way Analysis of Variance (ANOVA) followed by Dunnett’s post hoc test for between group significance.