Table 2. Analysis of lipid processing enzymes intensities performed by two way ANOVA.

Statistical significance is shown for the source of variation (HIF1-α, O₂ tension or their interaction); the statistical significance within the groups is shown after Bonferroni multiple comparisons post-test analysis. Abbreviations: 1, HCT116 wild type 21% O₂; 2, HCT116 hif1α^−/− 21% O₂; 3, HCT116 wild type 1% O₂; 4, HCT116 hif1α^−/− 1% O₂. NS, not significant.

Enzyme	Source of Variation (p-value)			Bonferroni multiple comparisons Post-test analysis
	HIF1-α	O2 tension	Interaction
Acetyl-CoA Carboxylase	<0.0001	0.001	NS	1-2: <0.001; 1-3: <0.001; 2-4: <0.001; 3-4: <0.01
Acetyl-CoA actyltransferase	<0.0001	NS	NS	1-2: <0.001; 3-4: <0.001
Stearoyl-CoA desaturase	NS	<0.0001	NS	1-3: <0.01; 2-4: <0.001; 3-4: <0.01
Phospholipase D3	NS	<0.001	NS	1-3: <0.05; 2-4: <0.001