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Blood vessel occlusions were found in the lungs of 100-day-old ku70−/− mice. Immunohistochemical staining with the endothelial cell marker, von Willebrand Factor (vWF), in (a) WT and (B) ku70−/− showed the presence of pulmonary arterial occlusions only in ku70−/− mice. Ku70−/− mice also developed plexiform-like lesions around the occluded vessel (circled). (c) The table summarizes the number of mice in each genetic background that developed blood vessel occlusion by 100 days of age
