Table 1. The somatic mutations of SPOP identified in exome sequencing of endometrial cancers.

	Amino-acid change	Mutation types	Histological subtypes	ratios	Reference
1	G75R	Missense	Serous	10% (1/10)	Kuhn E et al.6
2	M117V D140G	Missense	Serous	5.9% (2/34)	Zhao S et al.5
3	E47K S80R P94A M117I R121Q	Missense	Serous Clear cell	8% (4/52) 9% (2/23)	Le Gallo M et al.7
4	E50K M117I R121Q D140G	Missense	Endometrioid Serous	5.7% (10/175) 7% (3/43)	Kandoth C et al.4