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. 2015 Mar 26;6(3):e1703. doi: 10.1038/cddis.2015.61

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Copyright © 2015 Macmillan Publishers Limited

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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NF-κB activation is required in TSP50-induced cell migration and invasion. (a) Top panel: Overexpression of IκB-SR. Bottom panel: Overexpression of IκB-SR suppressed TSP50-induced p65 nuclear translocation by immunofluorescence assay. (b) Overexpression of IκB-SR suppressed TSP50-induced cell migration. Scale bar, 100 μm. (c) Overexpression of IκB-SR suppressed TSP50-induced cell invasion. Scale bar, 50 μm. (d) Overexpression of IκB-SR suppressed TSP50-induced cell adhesion. Scale bar, 150 μm. (e) Effects of I κB-SR expression on the morphology of TSP50-expressing cells. The arrow points out the filopodium. Scale bar, 50 μm