. 2015 Feb 26;112(7):1157–1165. doi: 10.1038/bjc.2015.67

Table 3. Results for the receiver operator characteristic curve analysis for the test cohort in (A) and the validation cohort in (B), summarising the C-indices, the 95% confidence interval for the C-indices and the P-value for the discriminative ability.

	Area under curve (C-index)	95% confidence interval	P-value	Pairwise comparison to RMH model, P-value
(A) Test cohort
—RMH score	0.630	0.56–0.70	0.0002***	—
—Log₁₀NLR	0.583	0.52–0.65	0.02*	0.9
—RMH score+NLR50	0.583	0.57–0.70	0.0002***	0.06
—RMH score+Log₁₀NLR	0.647	0.58–0.71	<0.0001***	0.005**
(B) Validation cohort
—RMH score	0.545	0.56–0.65	<0.0001***	—
—Log₁₀NLR	0.573	0.52–0.62	0.004**	0.3
—RMH score+NLR50	0.611	0.56–0.66	<0.0001***	<0.0001***
—RMH score+Log₁₀NLR	0.623	0.57–0.67	<0.0001***	<0.0001***

Abbreviations: NLR=neutrophil–lymphocyte ratio; RMH=Royal Marsden Hospital.

The last column shows the non-parametric paired comparison of the C-indices to the RMH score. *P<0.05, **P<0.01, ***P<0.001.