Table 3. Correlation between change from baseline to C1D28 in monocyte count and plasma markers.
|
Correlation with change in monocytes, expressed as Spearman correlation coefficient (ρ)/P-value | |||
|---|---|---|---|
| Carcinoid tumour (n=37) | pNET (n=62) | All patients (N=99) | |
| Change in VEGF | −0.25/0.16 | −0.13/0.33 | −0.17/0.10 |
| Change in sVEGFR-2 | 0.130/0.46 | 0.31/0.01 | 0.19/0.07 |
| Change in sVEGFR-3 | 0.37/0.04 | 0.22/0.10 | 0.32/0.002 |
| Change in IL-8 | −0.06/0.75 | −0.10/0.45 | −0.07/0.53 |
Abbreviations: IL-8=interleukin 8; pNET, pancreatic neuroendocrine tumour; sVEGFR-2=soluble VEGF receptor 2; sVEGFR-3=soluble VEGF receptor 3; VEGF=vascular endothelial growth factor. Correlation coefficients with P-values ⩽0.05 are shown in bold.