Figure 2.

HEY1 promotes invasion of osteosarcoma cells. HEY1 siRNA-treated osteosarcoma cell lines or control siRNA-treated osteosarcoma cells were examined by using an invasion assay. Treatment with HEY1 siRNA decreased the expression of HEY1 mRNA. Column graphs show percent of invading cells after the invasion assay. Percent of invading cells in control siRNA-transfected cell lines were defined relative to an invasion of 100%. Representative photomicrographs show invaded cells (lower). Scale bar is 200 μm. *P< 0.05, Student's t-test.