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. 2015 Jan 16;308(7):L628–L638. doi: 10.1152/ajplung.00373.2014

Fig. 1.

Fig. 1.

Infection of SP-CGFP mice with influenza A/WSN/33 (H1N1) resulted in severe cachexia, hypoxemia, and pulmonary edema. Effect of intranasal infection of C57BL/6-congenic SP-CGFP mice with H1N1 influenza A/WSN/33 (10,000 FFU/mouse) on: body weight (BWT; %change from day 0; n > 10 mice/group, A); carotid arterial oxygen saturation (SaO2; n > 10/group, B); lung water content (wet-to-dry weight ratio; n = 5–6/group, C); and lung homogenate viral titers (log FFU/g; n = 5/group, D). SP-C, surfactant protein-C; GFP, green fluorescent protein; FFU, focus-forming units. *P < 0.05 and #P < 0.001 vs. uninfected mice. ¶P < 0.001 vs. 2 days postinfection (dpi). Data are presented as means ± SE.