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. 2015 Jan 16;308(7):L628–L638. doi: 10.1152/ajplung.00373.2014

Fig. 4.

Fig. 4.

Infection with influenza A virus reduced expression of SP-C protein and increased expression of podoplanin (PODO) protein by ATII cells isolated from SP-CGFP mice. A: composite Western blot for SP-C, surfactant protein-A (SP-A), surfactant protein-D (SP-D), and PODO proteins and H1N1 influenza A virus nucleoprotein (NP) in homogenates of ATII cells isolated from uninfected and influenza A/WSN/33 virus-infected SP-CGFP mice (no adjustments were made to original images other than conversion from color to grayscale). B: effect of infection with influenza A/WSN/33 virus on relative expression of SP-C protein in ATII cell homogenates. C: effect of infection with influenza A/WSN/33 virus on relative expression of PODO protein in ATII cell homogenates. D: effect of infection with influenza A/WSN/33 virus on relative NP expression in ATII cell homogenates; n = 3/group; normalized to GAPDH. *P < 0.05 and #P < 0.001 vs. uninfected mice. †P < 0.05 and ¶P < 0.001 vs. 2 dpi. Data are presented as means ± SE.