Fig. 6.
Number (No.) of BK channels in excised micro patches. The number of BK channels in inside/out patches was determined at +60 mV in symmetrical KCl solutions with 3 mM Ca2+ in the bath solution to ensure maximal channel activation. Patch electrode tip resistances averaged 15.5 ± 0.1 MΩ (n = 192). Frequency histograms of the number of BK channels per patch preparation with distribution curve overlays were displayed. A: LTH adult (n = 39); B: LTH near-term fetus (n = 45); C: normoxic adult (n = 44); and D: normoxic near-term fetus (n = 64).