Fig. 5.

Affymetrix microarrays were used to interrogate supraoptic nucleus (SON) from EU vs. 7-day SL animals (2% wt/vol) and revealed 9,843 genes (A) significantly regulated genes (Welch t-test, corrected using Benjamini-Hochberg to keep P < 0.05, S1), of which 1,108 genes (B) were regulated by greater than twofold (S2) between EU and SL. Microarrays comparing EU and 3-day WD in the SON were also compared, and 4,480 genes (S3) were regulated of which 106 genes (S4) were regulated by greater than twofold. In total, 2,783 genes (S5) were commonly regulated by both SL and WD in the rat SON, and 95 genes (S6) that were commonly regulated by greater than 2-fold (see supplementary Figs. S1–S6).