Table 3.
Associations of infant bfPWV at 2–6 weeks with indicators of iron status during pregnancy in the Baby VIP study
| Predictor | Change in infant bfPWV (m/s) |
||||||
|---|---|---|---|---|---|---|---|
| unadjusted | 95% CI | p | adjusteda | adjusted 95% CI | p | n (multi-variable model) | |
| Maternal sF at 12 weeks’ gestation (per 10-µg/l change) | 0.02 | –0.01, 0.1 | 0.2 | 0.02 | –0.01, 0.1 | 0.3 | 261 |
| Maternal iron depletion at 12 weeks’ gestation (sF <15 µg/l) | –0.2 | –0.5, 0.3 | 0.4 | –0.2 | –0.6, 0.2 | 0.3 | 261 |
| Maternal sTfR at 12 weeks’ gestation (nmol/l) | 0.03 | –0.004, 0.1 | 0.1 | 0 | –0.01, 0.04 | 0.3 | 261 |
| Maternal log R/F ratio at 12 weeks’ gestation (µg/l) | 0 | –0.1, 0.1 | 0.9 | 0 | –0.2, 0.1 | 0.5 | 261 |
| Maternal Hb at ≥20 weeks’ gestation (g/dl) | 0.1 | –0.1, 0.3 | 0.3 | 0.1 | –0.1, 0.2 | 0.6 | 253 |
| Maternal Hb at >20 weeks’ gestation (g/dl) | 0.2 | –0.001, 0.3 | 0.05 | 0.2 | –0.004, 0.3 | 0.06 | 256 |
| Maternal anaemia at ≥20 weeks’ gestation (<11 g/dl) | 0.7 | –0.1, 1.6 | 0.08 | 1.0 | 0.1, 1.9 | 0.02 | 253 |
| Maternal anaemia at >20 weeks’ gestation (<10.5 g/dl) | –0.1 | –0.5, 0.4 | 0.8 | 0.01 | –0.5, 0.5 | 0.9 | 256 |
a
Adjusted for baby's age, PWV measurement circumstances (position, feeding, asleep or awake, side), maternal age, smoking, gestational diabetes, preeclampsia, blood pressure at booking and 36 weeks’ gestation, deprivation score, and customised birth weight centile (takes into account maternal pre-pregnancy weight, height, ethnicity, parity, gestational age and baby's sex).