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Synthesis of prodrug, a three step process including amino group protection of amino acid using phthaloylation; reaction of acetaminophen with N-protected amino acid and finally the deprotection (DCC=N,N-dicyclohexylcarbodiimide, DMAP=4-dimethylaminopyridine, TFA=Trifluoroacetic acid, DCM=Dichloromethane)
