Table 1.
Intra- and inter-rater kappa statistics for PVS rating
| Sample | Brain region | Rater | Intra-rater kappa (95% CI) | Inter-rater kappa** (95% CI) |
|---|---|---|---|---|
| Aging study | Centrum semiovale | 1 | 0.68 (0.34–1.00) | 0.61 (0.39–0.81) |
| 2 | 0.70 (0.49–0.92) | |||
| Basal ganglia | 1 | 0.80 (0.66–0.94) | 0.80 (0.66–0.94) | |
| 2 | 0.76 (0.35–1.00) | |||
| Midbrain | 1 | 0.64 (0.01–1.00) | 0.51 (0.06–0.96) | |
| 2 | 0.58 (0.17–1.00) | |||
| Stroke study | Centrum semiovale | 1 | 0.75 (0.62–0.90) | 0.80 (0.67–0.93) |
| 2 | 0.74 (0.59–0.86) | |||
| Basal ganglia | 1 | 0.87 (0.79–0.95) | 0.90 (0.84–0.97) | |
| 2 | 0.80 (0.72–0.89) | |||
| Midbrain | 1 | 0.60 (0.25–0.96) | 0.52 (0.21-0.84) | |
| 2 | 0.79 (0.56–1.00) | |||
* Calculated using data from first rating.
**
Kappa statistics for centrum semiovale and basal ganglia PVS quadratically weighted; quadratic weighting not possible for midbrain PVS due to only two possible categories for PVS rating.