Table 1. Demographic characteristics and baseline laboratory measures, including C-reactive protein (CRP) concentrations, in living and deceased sub-groups (based on vital status at about 7 years).
Living (n = 686) | Deceased (n = 160) | P | |
---|---|---|---|
Age | 61.5 ± 8.6 | 66.3 ± 9.1 | < 0.0001 |
Gender (%male) | 47.1% | 56.3% | 0.0432 |
Diabetes duration (years) | 10.1 ± 6.9 | 13.3 ± 8.2 | < 0.0001 |
BMI (kg/m2) | 32.5 ± 6.4 | 30.9 ± 6.4 | 0.0060 |
Hypertension (%) | 87.9% | 92.5% | 0.1250 |
Self-reported previous cardiovascular disease (%) | 36.4% | 58.8% | < 0.0001 |
Smoking – past or current (%) | 57.9% | 63.1% | 0.2464 |
Current medication use | |||
Insulin | 23.6% | 40.0% | < 0.0001 |
Oral hypoglycaemics | 80.5% | 75.0% | 0.1290 |
Lipid lowering medications | 47.6% | 45.8% | 0.7788 |
Anti-hypertensives | 77.8% | 86.3% | 0.0221 |
Serum glucose (mmol/l) | 8.12 ± 2.94 | 8.44 ± 3.82 | 0.8229 |
HbA1C (%, mmol/mol) | 7.4 ± 1.4 (50 ± 20) | 7.7 ± 1.9 (52 ± 26) | 0.0797 |
Total cholesterol (mmol/L) | 4.68 ± 1.30 | 4.73 ± 1.15 | 0.9726 |
HDL cholesterol (mmol/l) | 1.12 ± 0.31 | 1.07 ± 0.33 | 0.1088 |
LDL cholesterol (mmol/l) | 2.62 ± 0.83 | 2.68 ± 0.84 | 0.4585 |
Triglycerides (mmol/L) | 2.32 ± 1.47 | 2.44 ± 1.74 | 0.7970 |
Coronary artery calcified plaque (Agatston Score) | 1555 ± 3353 | 3360 ± 3467 | < 0.0001 |
CRP (mg/L) | 5.36 ± 7.91 | 9.37 ± 15.94 | < 0.0001 |
CRP risk groups | |||
Low (< 1 mg/l) | 19.4% | 14.4% | 0.0016 |
Medium (1–3 mg/l) | 34.1% | 24.4% | |
High (3–10 mg/l) | 30.9% | 32.5% | |
Very high (> 10 mg/l) | 15.6% | 28.8% | |
Follow-up duration (years) | 7.9 ± 1.5 | 4.8 ± 2.5 | < 0.0001 |
All P-values < 0.05 were in bold typeface.