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. 2015 Mar 22;2015:301635. doi: 10.1155/2015/301635

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Copyright © 2015 José Eduardo Vargas et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Centrality analysis (a and b) of the major CP-PPI network. Dashed lines represent the threshold value calculated for each centrality. Proteins are represented by black dots, while flavonoid compounds are marked in red. Only proteins or flavonoid compounds with bottleneck scores above the network average are indicated. Legend: hub-bottleneck (H-B); non-hub-bottleneck (NH-B). FLA Compounds abbreviations: resveratrol (RESV); apigenin (APG); quercetin (QUER); myricetin (MYR); tricetin (TRIC), and genistein (GEN).