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Effects of MitoQ on ROS responses in isolated pancreatic acinar cells. (a) 1 mM H2O2 induced a steady rise of intracellular ROS production, indicated by an increase in DFDCA fluorescence, which was significantly reduced by 1 μM MitoQ but not dTPP. (b) Neither 1 μM MitoQ nor dTPP caused ROS production per se. (n ≥ 3 mice per group). DCFDA fluorescent traces are shown as normalised (F/F 0) mean ± SEM.
