Table 2. Mean percentages of thymic and central naive T-cell subtypes during the first year of life according to gender (n=62 males, n=68 females).
|
Birth |
6 months |
12 months |
Overall (longitudinal)a |
|||||
|---|---|---|---|---|---|---|---|---|
| Male | Female | Male | Female | Male | Female | Male | Female | |
| As % of CD4+ T cells | ||||||||
| CD31+ thymic naive | 74.9 | 77.3 | 72.1 | 74.1 | 66.6 | 67.6 | −1.8 (95% CI, −3.4, 0.3) | |
| P-value | 0.018 | 0.024 | 0.37 | 0.021 | ||||
| CD31− central naive | 18.5 | 16.3 | 12.4 | 9.5 | 12.5 | 10.1 | 2.6 (95% CI, 1.4, 3.7) | |
| P-value | 0.011 | <0.001 | <0.001 | <0.001 | ||||
| Thymic/central naive ratio | 4.6:1 | 5.2:1 | 6.5:1 | 8.7:1 | 6.0:1 | 7.7:1 | −1.2 (95% CI, −1.9, 0.5) | |
| P-value | 0.056 | <0.001 | 0.001 | 0.002 | ||||
Abbreviation: CI, confidence interval.
Mean difference (male to female).