Table 4.

Cox proportional hazard models (hazard ratio, 95% condifence interval)^* between C-reactive protein and lipid profile measures for the prediction of mortality during the follow-up.

	Overall sample n=336		Age < 85 years old n=188		Age ≥ 85 years old n=148
	HR (95%CI)	p	HR (95%CI)	p	HR (95%CI)	p
C-reactive protein	2.97 (1.31–6.72)	0.009	3.22 (0.80–12.91)	0.10	3.24 (1.02–10.29)	0.04
Total cholesterol	0.72 (0.55–0.94)	0.02	0.62 (0.38–0.99)	0.05	0.72 (0.50–1.04)	0.09
C-reactive protein	3.18 (1.38–7.30)	0.007	3.31 (0.79–13.90)	0.10	3.69 (1.12–12.11)	0.03
HDL cholesterol	0.78 (0.56–1.07)	0.12	0.76 (0.46–1.26)	0.29	0.80 (0.50–1.28)	0.36
C-reactive protein	3.06 (1.35–6.95)	0.008	3.14 (0.77–12.75)	0.11	3.42 (1.08–10.92)	0.04
LDL cholesterol	0.78 (0.60–1.02)	0.07	0.77 (0.46–1.28)	0.31	0.74 (0.53–1.04)	0.09
C-reactive protein	3.21 (1.41–7.34)	0.006	2.95 (0.70–12.42)	0.14	4.13 (1.34–12.72)	0.01
Triglycerides	0.85 (0.66–1.10)	0.23	0.62 (0.37–1.02)	0.06	0.84 (0.60–1.18)	0.31

^*Adjusted for gender, body mass index, current smoking, physical activity level, coronary heart disease, congestive heart failure, cerebrovascular disease, diabetes, hypertension, peripheral artery disease, cancer, non-steroidal antiinflammatory drugs, statins, albumin.

Biomarker concentrations are expressed per standard deviation (SD) increase.

SDs: total cholesterol 44.74 mg/dL; LDL cholesterol 38.77 mg/dL; HDL cholesterol 13.46 mg/dL; triglycerides (log value of mg/dL) 0.42; C-reactive protein (log value of mg/L) 2.63.

C-reactive protein and each lipid profile measures are simultaneously included in separate models.