Table 2.
Findings in European-Americans
| chr | chr.pos | Marker | Effect Allele | Ref Allele | MAF | Type | Gene | Yale-Penn p | SAGE p | Meta p | Meta Adjusted p |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 7 | 82157289 | rs35653049 | C | T | .05 | NA | NA | 1.30E-01 | 1.39E-08 | 4.44E-07 | 4.56E-08 |
| 7 | 82159767 | rs12532806 | G | A | .05 | NA | NA | 1.47E-01 | 1.17E-08 | 4.91E-07 | 3.96E-08 |
| 7 | 82158523 | rs13225753 | G | A | .05 | NA | NA | 1.37E-01 | 1.78E-08 | 5.28E-07 | 3.48E-08 |
| 7 | 82163223 | rs12535073 | G | A | .05 | NA | NA | 1.60E-01 | 1.17E-08 | 6.38E-07 | 5.08E-08 |
| 7 | 82154194 | rs12532927 | C | T | .05 | NA | NA | 1.23E-01 | 3.47E-08 | 7.67E-07 | 9.95E-08 |
| 7 | 82151812 | rs10486966 | G | A | .05 | NA | NA | 1.22E-01 | 4.62E-08 | 8.97E-07 | 1.54E-07 |
| 7 | 82149544 | rs35521884 | T | C | .05 | NA | NA | 1.22E-01 | 6.12E-08 | 1.07E-06 | 1.72E-07 |
| 7 | 82165099 | rs35763698 | A | G | .05 | NA | NA | 2.15E-01 | 1.07E-07 | 5.70E-06 | 4.48E-07 |
| 15 | 78961282 | rs199970818 | A | AAAAAT | .40 | NA | NA | 4.74E-04 | 2.57E-02 | 2.73E-05 | 2.72E-07 |
Summary of significant results and also results up to p = 5 × 10−7. All study and population specific results were corrected for their respective genomic inflation factors. Only those rows are shown where the marker allele frequency was >.02. Top GWAS results, those that meet genome-wide significance are in bold.
chr, chromosome; chr.pos, chromosome position base pairs; GWAS, genome-wide association study; MAF, minor allele frequencies; NA, not applicable; Ref, reference; SAGE, Study of Addiction: Genetics and Environment.