Figure 3.

Ca²⁺ wave propagation is sensitive to the density of IP₃R. From left to right, the three red dots in c–f correspond to features of the following Ca²⁺ waves: (a) low IP₃R density (0.9× baseline); baseline IP₃R density (Fig. 2); (b) high IP₃R density (1.8× baseline). (c) time to wave onset (0 indicates no wave), (d) wave propagation speed, (e) duration (2× Ca²⁺ elevation; median duration across dendritic locations) (f) peak amplitude. (c–f each show 91 different equally spaced parameter values) (Colorscale in (a) and (b) same as in Fig. 2.)