Table 2.
BoNT-A medication treatment cost and dosagea
| BoNT-A | Mean | Range
|
Source | |
|---|---|---|---|---|
| Min | Max | |||
| AbobotulinumtoxinA | ||||
| Vial cost of abobotulinumtoxinA (300 units) | £92.40 | NA | NA | BNF24 |
| Vial cost of abobotulinumtoxinA (500 units) | £154.00 | NA | NA | BNF24 |
| Maximum recommended dosage per injection of abobotulinumtoxinA | 1,000 units | 1,000 units | 1,000 units | UK SPC Dysport®28 |
| OnabotulinumtoxinA | ||||
| Vial cost of onabotulinumtoxinA (50 units) | £77.50 | NA | NA | BNF24 |
| Vial cost of onabotulinumtoxinA (100 units) | £138.20 | NA | NA | BNF24 |
| Vial cost of onabotulinumtoxinA (200 units) | £276.40 | NA | NA | BNF24 |
| Maximum recommended dosage per injection of onabotulinumtoxinA | 360 units | 360 units | 360 units | UK SPC Botox®27 |
| IncobotulinumtoxinA | ||||
| Vial cost of incobotulinumtoxinA (50 units) | £72.00 | NA | NA | BNF24 |
| Vial cost of incobotulinumtoxinA (100 units) | £129.90 | NA | NA | BNF24 |
| Maximum recommended dosage per injection of incobotulinumtoxinA | 400 units | 400 units | 400 units | UK SPC Xeomin®29 |
Note:
a
Maximum recommended doses were chosen for this base case because in the UK, SPC are not alike in terms of muscle segments injected.
Abbreviations: BNF, British National Formulary; BoNT-A, botulinum toxin A; SPC, Summary of Product Characteristics; UK, United Kingdom.