Table 3.

Resource use for BoNT-A and best supportive care arms

Resource use item	BoNT-A arm		Best supportive care arm		Source
	% Using	Amount	% Using	Amount
Skeletal muscle relaxant
Oral baclofen	3%	60 mg daily dose	70%	60 mg daily dose	Ward et al;19 BNF24
Tizanidine	3%	24 mg daily dose	70%	24 mg daily dose	Ward et al;19 BNF24
Oral dantrolene	3%	225 mg daily dose	70%	225 mg daily dose	Ward et al;19 BNF24
Analgesics
Benzodiazepines	5%	208 mg daily dose	5%	208 mg daily dose	KOL opinion
Gabapentin	5%	600 mg daily dose	5%	600 mg daily dose	KOL opinion
Health care professional
Physiatrist	50%a	4.3 visits per year, lasting 1 hour each timeb	50%a	4.6 visits per year, lasting 0.5 hour each time	Assumptions; Ward et al19
Neurologist	50%a	4.3 visits per year, lasting 1 hour each timeb	50%a	1.9 visits per year, lasting 0.5 hour each time	Assumptions; Ward et al19
Physiotherapist	100%	140 visits per year, lasting 1 hour each timeb	100%	166 visits per year, lasting 0.5 hour each time	KOL opinion; Ward et al19
Practice nurse	100%	156 visits per year	100%	296 visits per year	KOL opinion; Ward et al19
GP visit	100%	2.4 visits per year	100%	4.9 visits per year	KOL opinion; Ward et al19
Laboratory test
Blood test	0%	0	70%	4 times per year	KOL opinion
Procedures
Ultrasound	12.50%	4.3 times per yearb	0%	0	KOL opinion, assumption
Splinting	50%	3 times per year	50%	3 times per year	KOL opinion
Nonmedical costs
Transportation	50%	4.3 times per yearb	50%	4.6 times per yearc	Assumption
Other medical/social services costs
Hospital admission days	100%	2.5 times per year	100%	2.5 times per year	KOL opinion

Notes:

^aPatients are treated by either a physiatrist or a neurologist, therefore 50% of patients are assumed to visit a physiatrist and 50% a neurologist;

^bassumed outpatient visit is linked to the number of injections per year (BoNT-A injection provided every 12 weeks);

^cassumed transportation is linked to the number of physiatrist visits.

Abbreviations: BNF, British National Formulary; BoNT-A, botulinum toxin A; GP, general practitioner; KOL, key opinion leader.